Three New Pyridine Alkaloids from Vinca major Cultivated in Pakistan
نویسندگان
چکیده
منابع مشابه
Vinca Alkaloids
Vinca alkaloids are a subset of drugs obtained from the Madagascar periwinkle plant. They are naturally extracted from the pink periwinkle plant, Catharanthus roseus G. Don and have a hypoglycemic as well as cytotoxic effects. They have been used to treat diabetes, high blood pressure and have been used as disinfectants. The vinca alkaloids are also important for being cancer fighters. There ar...
متن کاملThe Vinca Alkaloids: a New Class of Oncolytic Agents.
A phytochemical investigation of the plant Vinca ro@eaLinn. has demonstrated that a number of alkaloidal substances can be obtained with antitumon activity. Over 30 alkaloids have been obtained, of which four—vinbiastine, vinleunosine, vincnistine, and vinrosidine—are known definitely to be active. Chemically these compounds are closely related to one another and to two monomeric alkaloids,...
متن کاملDeath and Neurological Devastation From Intrathecal Vinca Alkaloids.
Inadvertent intrathecal vincristine administration causes fatalities.
متن کاملPyridine alkaloids from a Parthenium hybrid.
Two pyridine alkaloids were isolated from the derubberized resin of the hybrid Parthenium argentatum x P tomentosa. These alkaloids are (+/-)-N-[4-(1-aminoethyl) phenyl]-4-[3-methylbutenylidine]-1,4-dihydropyridine (guayulamine A) and (+/-)-N-[4-(1-aminoethyl) phenyl]-4-[4-methylpentenylidine]-1, 4-dihydropyridine (guayulamine B). The structures were established by one- and two-dimensional NMR ...
متن کاملPhytochemical Investigation of Vinca Minor Cultivated in Iran
Lesser Periwinkle (Vinca minor L.), a member of Apocynaceae, is not only an ornamental plant with lilac-blue flowers, but also a medical plant producing an important alkaloid, vincamine, found in the leaves which shows a pronounced cerebrovasodilatory and neuroprotective activity. This plant is native to northern Spain, western France, central and southern Europe, and Caucasus. It has been rece...
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ژورنال
عنوان ژورنال: Natural Products and Bioprospecting
سال: 2017
ISSN: 2192-2195,2192-2209
DOI: 10.1007/s13659-017-0137-7